The Oxford Biblical Studies Online and Oxford Islamic Studies Online have retired. Content you previously purchased on Oxford Biblical Studies Online or Oxford Islamic Studies Online has now moved to Oxford Reference, Oxford Handbooks Online, Oxford Scholarship Online, or What Everyone Needs to Know®. For information on how to continue to view articles visit the subscriber services page.

Related Content

More Like This

Show all results sharing these subjects:

  • Science and technology
  • Life Sciences


Show Summary Details


Gaucher disease

Quick Reference

A genetically determined (autosomal recessive) disease resulting from the deposition of glucocerebrosides (see cerebroside) in the brain and other tissues (especially bone). It results in mental retardation, abnormal limb posture and spasticity, and difficulty with swallowing. Carrier detection and preimplantation genetic diagnosis are possible; enzyme replacement therapy may be used in treatment. P. C. E. Gaucher (1854–1918), French physician

Reference entries

View all reference entries »