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2,3,7,8-Tetrachlorodibenzodioxin, a member of the family of dioxin compounds that was a contaminant in a broad-leaf herbicide used to kill weed trees, and as agent orange, used in massive quantities by the US forces in Vietnam in the late 1960s and early 1970s. It is a carcinogen, a mutagen, and a teratogen. Its manufacture and use ceased in the late 1970s, but the delayed after effects, notably malignant disease, continued to occur for several decades.

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