Related Content

Related Overviews


'SUFU' can also refer to...


More Like This

Show all results sharing this subject:

  • Medicine and health


Show Summary Details



Quick Reference

The major negative regulator of the sonic hedgehog/*patched signalling pathway in vertebrates (suppressor of fused). The human gene has 40% homology with the Drosophila gene and the product (484 aa) inhibits the transcriptional activity of gli-1 (glioma-associated oncogene-1) and osteogenic differentiation in response to sonic hedgehog signalling.

Reference entries