The consistent use of knowledge derived from biological, clinical, and epidemiological research in the management of patients, with particular attention to the balance of benefits, risks, and costs of diagnostic tests, screening programs, and treatment regimens, taking account of each patient’s circumstances, including baseline risk, comorbid conditions, culture, and personal preferences.^{6, 9, 58, 202, 203, 302} There are no major intellectual reasons either against Evidence-Based (EB) nursing, EB health care planning,⁵⁸ EB proteomics,^{91, 434, 435} or, for that matter, EB justice and EB economics.