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date: 22 September 2020


A Dictionary of Biomedicine

John Lackie

A cytoplasmic zinc finger protein (790 aa) that inhibits *NFκB activity and TNF-mediated programmed cell death. The expression of the A20 mRNA is upregulated by TNFα. It is a dual function enzyme with deubiquitinating and ubiquitin ligase activity that triggers degradation of RIP (... ...

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