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date: 03 August 2020

epidermal growth factor (EGF) 

A Dictionary of Biomedicine

John Lackie

, Brian NationBrian Nation

A mitogenic polypeptide (53 aa) cleaved from the 1207-aa pro-EGF (urogastrone) initially isolated from male mouse submaxillary gland and also found in urine. The name derives from the early bioassay, but EGF is active on a variety of cell types, especially but not exclusively epithelial. A family of similar growth factors are now recognized. The ... ...

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