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date: 04 August 2020

cystic fibrosis 

A Dictionary of Biomedicine

John Lackie

, Brian NationBrian Nation

An autosomal recessive disorder of exocrine gland secretion that affects multiple systems, most notably the lung, where the abnormally thick mucus is not cleared well and there is a predisposition to respiratory infections. There are also effects on the pancreas, where blockage of the ducts can cause cysts and there may be a shortage of digestive enzymes. There are also effects in the bowel, biliary tree, and sweat glands. The cystic fibrosis transmembrane conductance regulator (CFTR) is an ... ...

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