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hedgehog

In the Bestiaries it is said to gather fruit for its young by impalement on its spines; it may thus be taken to exemplify prudence, or as an image of the Devil harvesting unwary souls. ...

hedgehog

hedgehog   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...hedgehog A secreted morphogen originally discovered in Drosophila ; various mammalian homologues have subsequently been identified ( sonic hedgehog (462 aa), Indian hedgehog (411 aa), and desert hedgehog (396 aa), all of which are involved in patterning of the embryo. The protein precursors are autoprocessed to produce ~20-kDa N-terminal portions that are active in the hedgehog signalling pathway which, if perturbed, can disrupt organ development and cause various degenerative and neoplastic human diseases. Further processing of the active portion...

hedgehog

hedgehog   Reference library

The Oxford Dictionary of Christian Art and Architecture (2 ed.)

Reference type:
Subject Reference
Current Version:
2013
Subject:
Art & Architecture, Religion
Length:
61 words

... According to the Bestiaries , the hedgehog lies on its back to impale grapes or other fruits on its spines. It then takes them home to feed its young. Two morals can be drawn: the first, that it exemplifies the virtue of Prudence; and the second, that it symbolizes the Devil, picking off half-hearted souls and making away with...

hedgehog

hedgehog   Quick reference

The Diner’s Dictionary (2 ed.)

Reference type:
Subject Reference
Current Version:
2013

... A dessert dish poplar in England in the eighteenth and nineteenth centuries in which a vaguely hedgehog-shaped cooked base made from eggs, butter, cream, sugar, and ground almonds had sharp slivers of almond inserted all over its surface, giving the appearance of erinaceous spines. The concept survived into the twentieth century, reapplied to cakes: Good Housekeeping’s Cookery Book ( 1960 ), for example, gave a recipe for ‘Hedgehog cake’. Compare porcupine...

hedgehog

hedgehog   Reference library

The Oxford Companion to Food (3 ed.)

Reference type:
Subject Reference
Current Version:
2014

...chicken or sucking pig. Fernie ( 1905 ) provides alternative methods of cooking, and cites the Tramp’s Handbook ( 1905 ) as evidence that hedgehogs are nice and fat at Michaelmas, when they have been feeding on windfall crabapples. He adds, but without giving a source, that in France the foresters of the marquis de Cherville were given to concoct a delicious stew of hedgehog with morels . The ‘hedgehog pudding’ which formerly enjoyed some popularity in England, notably in the 18th century but also in the 19th, was so called because of the slivered...

hedgehog

hedgehog   Quick reference

World Encyclopedia

Reference type:
Subject Reference
Current Version:
2004
Subject:
Encyclopedias
Length:
45 words

... Small, nocturnal Eurasian mammal of the family Erinaceidae. It has short, sharp spines above, lighter-coloured fur below, and a pointed snout. It feeds on insects and other small animals, and defends itself by rolling into a ball with the spines outermost. Species Erinaceus europaeus...

hedgehog

hedgehog n.   Reference library

The Oxford Essential Dictionary of the U.S. Military

Reference type:
Subject Reference
Current Version:
2002

... n. 1 an obstacle made of barbed wire strung on frames. 2 an anti-submarine weapon developed in 1943 which consists of multiple mortar tubes which throw contact-fused anti-submarine depth charges in a pattern from the deck of a sub-hunting surface...

hedgehog

hedgehog   Quick reference

Mike Allaby

Dictionary Plus Science and Technology

Reference type:
Subject Reference
Current Version:
2016
Subject:
Science and technology
Length:
72 words

... A small, omnivorous, mainly nocturnal mammal with hairs on the back and sides that are hollow and stiffened with keratin to form sharp spines. If the animal is disturbed it rolls into a ball, with its spines on the outside and its vulnerable head and belly safely inside. There are five genera with 17 species found in parts of Europe, Asia, and North America, and introduced in New Zealand. Mike...

Indian hedgehog

Indian hedgehog   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...Indian hedgehog ( Ihh ) One of the hedgehog family of morphogens, involved in endochondral bone formation. Mutations in the Indian hedgehog gene cause brachydactyly type A1...

sonic hedgehog

sonic hedgehog   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...sonic hedgehog A secreted morphogen (465 aa) that is the inductive signal for patterning of the ventral neural tube, the anterior–posterior limb axis, and the ventral somites . Defects in shh or in its signalling pathway are a cause of holoprosencephaly 3 and VACTERL syndrome . See desert hedgehog ; hedgehog ; Indian hedgehog...

hedgehog protein

hedgehog protein   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
24 words

... protein a transmembrane protein involved in segment polarity and cell‐to‐cell signalling during embryogenesis and metamorphosis in Drosophila melanogaster . See also sonic hedgehog proteins...

Sonic hedgehog

Sonic hedgehog   Reference library

A-Z of Plastic Surgery

Reference type:
Subject Reference
Current Version:
2009
Subject:
Medicine and health, Surgery
Length:
55 words

...hedgehog Implicated in limb development in the AP plane. Sonic hedgehog ( Shh ) is a segment polarity gene. It is expressed in the posterior mesenchyme of limb buds. It patterns the AP limb axis. It may maintain the progress zone of the AER while acting as a positional signal along the AP axis. See Embryology...

Sonic hedgehog

Sonic hedgehog   Quick reference

A Dictionary of Biology (8 ed.)

Reference type:
Subject Reference
Current Version:
2019
Subject:
Science and technology, Life Sciences
Length:
191 words

...hedgehog ( SHH ) A protein that has a crucial role in patterning and development of tissues in vertebrates, particularly of the nervous and skeletal systems. It is homologous to Hedgehog protein , which performs a similar function in the fruit fly Drosophila —Hedgehog was so named because mutation of its gene in Drosophila produced flies bearing spiky denticles resembling the spines of a hedgehog. Sonic hedgehog, named after a video game character, is one of three proteins belonging to the Hedgehog family in vertebrates—the others being Desert hedgehog...

hedgehog (hh)

hedgehog (hh)   Quick reference

A Dictionary of Genetics (8 ed.)

Reference type:
Subject Reference
Current Version:
2014
Subject:
Science and technology, Life Sciences
Length:
55 words

... (hh) a segment polarity gene of Drosophila located at 3–81.2. This selector gene ( q.v. ) is responsible for the proper development of both wings and legs. Homologs of hh have been found in fish, birds, and mammals. In dolphins and whales, the hindlimbs are suppressed because hh is not expressed. See Sonic hedgehog (Shh)...

desert hedgehog

desert hedgehog   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...desert hedgehog One of the hedgehog family of conserved signalling molecules that coordinate various patterning processes during early embryonic development. Desert hedgehog (Dhh, 396 aa) is restricted, in the developing mouse, to Sertoli cells of developing testes and Schwann cells of peripheral nerves. The precursor molecule is autocatalytically cleaved and the C-terminal product covalently attaches a cholesterol moiety to the soluble N-terminal product that contains the signalling activity, restricting it to the cell surface. Defects in Dhh have been...

sonic hedgehog proteins

sonic hedgehog proteins   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
50 words

...hedgehog proteins analogues of hedgehog protein found in zebrafish and chickens, and involved (in the latter case) in limb‐bud pattern formation. The hedgehog proteins thus appear to be vital to pattern formation in several metazoan groups. The name sonic hedgehog is an allusion to a children's animated cartoon...

hedgehog signalling complex

hedgehog signalling complex   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...hedgehog signalling complex The multiprotein complex downstream of smoothened that has been most extensively characterized in Drosophila , but which probably has a homologue in humans. It is a tetrameric microtubule-associated complex involving the kinesin-related protein Costal2 (Cos2), the protein kinase fused (Fu), and the transcription activator cubitus interruptus (Ci), the mammalian homologues of which are the Gli family. See hedgehog ; smoothened ; sonic hedgehog . hedgehog signalling complex A mini-review of the hedgehog signalling...

Sonic hedgehog (Shh)

Sonic hedgehog (Shh)   Quick reference

A Dictionary of Genetics (8 ed.)

Reference type:
Subject Reference
Current Version:
2014
Subject:
Science and technology, Life Sciences
Length:
42 words

...hedgehog (Shh) the vertebrate homolog of the Drosophila gene hedgehog ( q.v. ). In humans Shh has been mapped to 7q36. Shh encodes a signal protein that controls the patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral...

hedgehog

hedgehog n. 1   Reference library

Green's Dictionary of Slang

Reference type:
Subject Reference
Current Version:
2011
Subject:
Language reference
Length:
78 words

... n. 1 1 veal [the two meats are supposedly not dissimilar when cooked] . 1858 A. Mayhew Paved with Gold 105: On such occasions, bits of jelly were termed ‘size,’ and ‘fricandeau de veau’ was familiarly spoken of as ‘hedgehog’. 2 an unattractive woman. 1971 Current Sl. VI. 1975 G. Underwood ‘Razorback Sl.’ in AS L 1/2 61: hedgehog n Overweight, unattractive female. 2003 McGill Reed Dict. of N.Z. Sl. 100: hedgehog […] 2. Radical feminist. Late...

hedgehog

hedgehog n. 2   Reference library

Green's Dictionary of Slang

Reference type:
Subject Reference
Current Version:
2011
Subject:
Language reference
Length:
27 words

... n. 2 [rhy. sl. = wog n. 1 (1)] a derog. term for a foreigner, esp. a black or Asian person. 1992 R. Puxley Cockney Rabbit...

hedgehog

hedgehog   Quick reference

The Oxford Dictionary of Phrase and Fable (2 ed.)

Reference type:
Subject Reference
Current Version:
2006

... in the Bestiaries it is said to gather fruit for its young by impalement on its spines; it may thus be taken to exemplify prudence, or as an image of the Devil harvesting unwary...

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