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Overview

dopamine

A catecholamine that is a precursor in the synthesis of noradrenaline and adrenaline. It also functions as a neurotransmitter, especially in the brain.

dopamine

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A Dictionary of Chemistry (8 ed.)

Reference type:
Subject Reference
Current Version:
2020
Subject:
Science and technology, Chemistry
Length:
27 words
Illustration(s):
1

... A catecholamine that is a precursor in the synthesis of noradrenaline and adrenaline . It also functions as a neurotransmitter in the brain. ...

dopamine

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A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...which dopamine is the neurotransmitter. The dopamine uptake transporter (sodium-dependent dopamine transporter, solute carrier family 6 member 3, 620 aa), which is inhibited by cocaine , terminates the action of dopamine by reuptake into presynaptic...

dopamine

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The Oxford Dictionary of Sports Science & Medicine (3 ed.)

Reference type:
Subject Reference
Current Version:
2007
Subject:
Science and technology, Medicine and health
Length:
104 words
Illustration(s):
1

... A metabolic neurotransmitter belonging to the biogenic amines and is classified as a stimulant, but it is not on the World Anti-Doping Agency's Prohibited list. Dopamine is secreted by some sympathetic ganglia in the hypothalamus and by some neurones in the midbrain. It is the main neurotransmitter in extrapyramidal tracts . Its release is enhanced by amphetamines . High dopamine levels have been linked to aggression . Anti-psychotic drugs such as thorazine, have been used to block dopamine receptors and reduce aggression. However, overuse of...

dopamine

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A Dictionary of Biology (8 ed.)

Reference type:
Subject Reference
Current Version:
2019
Subject:
Science and technology, Life Sciences
Length:
27 words

...dopamine A catecholamine that is a precursor in the synthesis of noradrenaline and adrenaline . It also functions as a neurotransmitter, especially in the...

dopamine

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The Oxford Companion to the Body

Reference type:
Subject Reference
Current Version:
2003
Subject:
Science and technology, Life Sciences
Length:
348 words

...is converted to dopamine, and restores some lost functions. Another approach is to transplant fetal dopamine-secreting cells into the relevant brain nuclei to take over the function of the diseased nerve cells. Over-activity of dopaminergic nerves, especially in the limbic system, is associated with schizophrenia. It has also been claimed that individuals with mutations affecting the dopamine D 2 receptors show enhanced risk-taking behaviour. Some drugs, like the amphetamines, release dopamine from nerve endings in the brain, leading to hyperactivity and...

dopamine

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Concise Medical Dictionary (10 ed.)

Reference type:
Subject Reference
Current Version:
2020
Subject:
Medicine and health, Clinical Medicine
Length:
190 words

...rapid or irregular heartbeat, nausea, vomiting, breathlessness, angina pectoris, and kidney damage. Certain drugs (dopamine receptor agonists) have an effect on the body similar to that of dopamine. They include apomorphine , pergolide , ropinirole , cabergoline , and pramipexole and are used to treat parkinsonism . Drugs that compete with dopamine to occupy and block the dopamine receptor sites in the body are known as dopamine receptor antagonists . They include some antipsychotic drugs (e.g. the phenothiazines and butyrophenones ) and...

dopamine

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A Dictionary of Nursing (7 ed.)

Reference type:
Subject Reference
Current Version:
2017
Subject:
Medicine and health
Length:
68 words

...dopamine [ doh -pă-meen] n. a catecholamine derived from dopa that functions as a neurotransmitter, acting on specific dopamine receptors and also on adrenergic receptors throughout the body; it also stimulates the release of noradrenaline from nerve endings. Dopamine is used to increase the strength of contraction of the heart in heart failure, shock, severe trauma, and septicaemia. It is administered by intravenous infusion in carefully controlled...

dopamine

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A Dictionary of Dentistry (2 ed.)

Reference type:
Subject Reference
Current Version:
2020
Subject:
Medicine and health, Dentistry
Length:
41 words

... n. A catecholamine-derived neurotransmitter that transmits messages from one nerve cell to another in the nervous system. It is used in the treatment of shock, hypotension , and low cardiac output. It also stimulates the release of noradrenaline from nerve...

dopamine

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A Dictionary of Psychology (4 ed.)

Reference type:
Subject Reference
Current Version:
2015

... n. A biogenic amine and catecholamine that is one of the neurotransmitter substances significantly involved in central nervous system functioning, and that also functions as a hormone . Its three main pathways within the brain are from the midbrain to the basal ganglia ( see also Parkinson’s disease ), from the midbrain to the frontal lobes , and from the midbrain to the limbic system , the mesolimbic dopamine pathway being strongly implicated in experiences of pleasure or reward and also responses to salient stimuli in general. Formula:...

dopamine

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Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
45 words

... an alternative name for 3,4‐dihydroxyphenylethylamine; 3‐hydroxytyramine; 3,4‐dihydroxyphenylethylamine; 4‐(2‐aminoethyl)‐1,2‐benzenediol; a catecholamine neurotransmitter formed by aromatic‐ l ‐amino‐acid decarboxylase, EC 4.1.1.28, from 3,4‐dihydroxy‐ l ‐phenylalanine. A metabolic precursor of norepinephrine and epinephrine , it is found in dopaminergic nerves in the brain and in the adrenal medulla. See also Parkinson's disease...

dopamine antagonist

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A Dictionary of Psychology (4 ed.)

Reference type:
Subject Reference
Current Version:
2015

... antagonist n. Any drug such as olanzapine or one of the phenothiazines , butyrophenones , or dibenzodiazepines that inhibits the action of dopamine by blocking the dopamine receptors. See also antagonist ( 3 ) , neuroleptic ( 1 ) . Compare dopaminomimetic...

dopamine hypothesis

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Concise Medical Dictionary (10 ed.)

Reference type:
Subject Reference
Current Version:
2020
Subject:
Medicine and health, Clinical Medicine
Length:
34 words

... hypothesis the theory that schizophrenia is caused in part by abnormalities in the metabolism of dopamine and can be treated in part by drugs that antagonize its action as a...

dopamine transporter

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Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
36 words

... transporter an integral membrane protein of dopaminergic nerve terminals that permits re‐entry of dopamine in a Na + ‐ and Cl − ‐dependent manner. Cocaine binds strongly to, and inhibits, the transporter. A variety of mood‐modifying drugs act...

dopamine receptor

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Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
144 words

... receptor any protein that binds dopamine and mediates its intracellular effects. Types D 1 to D 5 have been recognized; D 1 and D 5 (also called D 1A and D 1B ) comprise one subfamily; D 2 , D 3, and D 4 (also called D 2A , D 2B , and D 2C ) comprise a second subfamily. D 3 receptors seem to be insensitive to guanine nucleotides and regulate conductance of Ca 2+ . All are G‐protein‐associated receptors. D 1 and D 5 elevate cyclic AMP, but vary in binding characteristics; D 2 has a short and a long form originating from alternative splicing; in...

dopamine β‐hydroxylase

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Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
51 words

... β ‐hydroxylase EC 1.14.17.1; recommended name : dopamine β ‐monooxygenase; systematic name : 3,4‐dihydroxyphenethylamine, ascorbate:oxygen oxidoreductase ( β ‐hydroxylating). An enzyme that catalyses hydroxylation of dopamine to norepinephrine in aminergic neurons releasing norepinephrine and epinephrine; ascorbate is simultaneously oxidized to dehydroascorbate. The enzyme is a copper protein, stimulated by fumarate. It is absent from dopaminergic...

N-arachidonoyl dopamine

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A Dictionary of Food and Nutrition (4 ed.)

Reference type:
Subject Reference
Current Version:
2014

...-arachidonoyl dopamine ( NADA ) An endocannabinoid formed by reaction between arachidonic acid and dopamine which acts mainly on the CB1 cannabinoid receptor...

dopamine neurons in the brain

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The Oxford Companion to the Mind (2 ed.)

Reference type:
Subject Reference
Current Version:
2006
Subject:
Science and technology, Psychology, Philosophy
Length:
670 words

...that there is a distinction between those symptoms in the Parkinsonian syndrome which are due to dopamine, and those due to non-dopamine neurons. Indeed, symptoms of hypokinesia can occur independently of rigidity and tremor. Hypokinesia can be successfully treated by giving the patient levodopa, an amino acid that is taken up in the brain and converted to the neurotransmitter dopamine in those dopamine neurons not affected by the disease. The other main dopamine subgroup of neurons innervates various nuclei in the limbic system, including the amygdala. They...

dopamine

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The New Oxford Dictionary for Scientific Writers and Editors (2 ed.)

Reference type:
Subject Reference
Current Version:
2009

... Abbrev.: ...

dopamine

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New Oxford Rhyming Dictionary (2 ed.)

Reference type:
Subject Reference
Current Version:
2013
Subject:
Language reference
Length:
128 words

... • gamine • bromine • thiamine • dopamine • amphetamine • histamine • quinine • strychnine • mezzanine • spalpeen • Philippine • lycopene • gangrene • terrene • silkscreen • windscreen • citrine • Dexedrine • putting green • Benzedrine • pseudoephedrine • Irene , polystyrene • widescreen • sight screen • chlorine , chorine, Doreen, Maureen, Noreen, taurine • smokescreen • rood screen • sunscreen • fluorine • helleborine • Gadarene • Hippocrene • glycerine ( US glycerin), nitroglycerine ( US nitroglycerin) • nectarine • wintergreen •...

dopamine

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The Canadian Oxford Dictionary (2 ed.)

Reference type:
English Dictionary
Current Version:
2005
Subject:
English Dictionaries and Thesauri
Length:
35 words

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