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Overview

cyclic AMP

A derivative of ATP that is widespread in cells as a second messenger in many biochemical reactions induced by hormones. Binding of the hormone to its receptor on the cell surface ...

cyclic AMP

cyclic AMP   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
12 words

... AMP or cAMP abbr. for adenosine 3′,5′‐phosphate. See also adenylate cyclase...

cyclic AMP

cyclic AMP   Quick reference

The Oxford Dictionary of Sports Science & Medicine (3 ed.)

Reference type:
Subject Reference
Current Version:
2007

... AMP An important intracellular chemical that mediates intracellular responses to some non-steroid hormones: it acts as a second messenger. Cyclic AMP is formed from ATP by the action of adenylate cyclase, an enzyme on the cell surface...

cyclic AMP

cyclic AMP n.   Quick reference

A Dictionary of Psychology (4 ed.)

Reference type:
Subject Reference
Current Version:
2015

... AMP n. Cyclic adenosine monophosphate, a compound widely distributed in biological cells that regulates reactions dependent on hormones and neurotransmitters and functions as a universal second messenger . cAMP abbrev. See also amp , creb...

cyclic AMP

cyclic AMP   Quick reference

A Dictionary of Chemistry (8 ed.)

Reference type:
Subject Reference
Current Version:
2020
Subject:
Science and technology, Chemistry
Length:
74 words

... AMP A derivative of ATP that is widespread in animal cells as a second messenger in many biochemical reactions induced by hormones. Upon reaching their target cells, the hormones activate adenylate cyclase, the enzyme that catalyses cyclic AMP production. Cyclic AMP ultimately activates the enzymes of the reaction induced by the hormone concerned. Cyclic AMP is also involved in controlling gene expression and cell division, in immune responses, and in nervous...

cyclic AMP

cyclic AMP   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...cyclic AMP ( cAMP ) An important second messenger , the 3′,5′-cyclic ester of AMP produced from ATP by the action of adenylate cyclase that is coupled to hormone receptors by GTP-binding proteins and is hydrolysed by a phosphodiesterase to produce 5′-AMP. It activates a cAMP-dependent protein kinase ( PKA ). It is also a morphogen (acrasin) for some slime...

cyclic AMP

cyclic AMP   Quick reference

A Dictionary of Genetics (8 ed.)

Reference type:
Subject Reference
Current Version:
2014
Subject:
Science and technology, Life Sciences
Length:
105 words

... AMP adenosine monophosphate with the phosphate group bonded internally to form a cyclic molecule; generated from ATP by the enzyme adenyl cyclase; abbreviated cAMP. Likewise, guanosine monophosphate (GMP) can become a cyclic molecule by a phosphodiester bond between 3′ and 5′ atoms. Cyclic AMP has been shown to function as an acrasin in slime molds and to be active in the regulation of gene expression in both prokaryotes and eukaryotes. In E. coli , cyclic AMP is required for the transcription of certain operons. See Appendix C , 1957, Sutherland and...

cyclic AMP

cyclic AMP   Quick reference

A Dictionary of Biology (8 ed.)

Reference type:
Subject Reference
Current Version:
2019
Subject:
Science and technology, Life Sciences
Length:
137 words

...cyclic AMP ( cAMP ; cyclic adenosine monophosphate ) A derivative of ATP that is widespread in cells as a second messenger in many biochemical reactions induced by hormones. Binding of the hormone to its receptor on the cell surface activates G proteins , which in turn activate (or in some cases inhibit) adenylate cyclase , the enzyme that catalyses the formation of cAMP. cAMP removes a regulatory subunit from the enzyme protein kinase A, thereby enabling it to phosphorylate (and hence activate) intracellular proteins that mediate the ultimate...

dibutyryl cyclic AMP

dibutyryl cyclic AMP   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...dibutyryl cyclic AMP ( db-cAMP ) An analogue of cAMP often used experimentally because it probably enters cells more readily and is less rapidly hydrolysed....

cyclic AMP phosphodiesterase

cyclic AMP phosphodiesterase   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
56 words

... AMP phosphodiesterase (number EC 3.1.4.17 shared with cyclic GMP phosphodiesterase ); recommended name : 3′,5′‐cyclic‐nucleotide phosphodiesterase; an enzyme that catalyses the hydrolysis of a nucleoside 3′,5′‐cyclic phosphate to a nucleoside 5′‐phosphate. The intracellular concentration of cyclic AMP is regulated by low‐affinity (type 1) and high‐affinity (type 2) enzymes. The enzymes are monomers; type 2 are well...

cyclic AMP receptor

cyclic AMP receptor   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
58 words

... AMP receptor any of various receptor molecules that bind cyclic AMP, especially CRP (def. 2), a bacterial catabolite (gene) activator protein. Other examples are the signalling receptors of the slime mould, Dictyostelium discoideum , which are similar to other eukaryotic G‐protein‐linked receptors. Receptor 1 is involved in aggregation, and receptor 2 is expressed after aggregation in pre‐stalk...

cyclic AMP‐dependent protein kinase

cyclic AMP‐dependent protein kinase   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
116 words

... AMP‐dependent protein kinase or protein kinase A ( abbr. : PKA) a protein kinase that is regulated by cyclic AMP (cAMP). In type I , the inactive form of the enzyme is composed of two regulatory and two catalytic subunits; activation by cAMP produces active catalytic monomers and a regulatory dimer with four bound cAMP molecules. Expression of regulatory subunits in some tissues is constitutive and in others is inducible. In type II , regulatory subunits mediate membrane association by binding to anchoring proteins, including the MAP‐2 kinase and ...

cyclic AMP

cyclic AMP   Reference library

The New Oxford Dictionary for Scientific Writers and Editors (2 ed.)

Reference type:
Subject Reference
Current Version:
2009

... AMP Short for adenosine 3′,5′-phosphate. Abbrev.: cAMP (lower-case...

cyclic AMP

cyclic AMP noun   Quick reference

New Oxford American Dictionary (3 ed.)

Reference type:
English Dictionary
Current Version:
2015
Subject:
English Dictionaries and Thesauri
Length:
54 words
cyclic AMP

cyclic AMP noun   Quick reference

Oxford Dictionary of English (3 ed.)

Reference type:
English Dictionary
Current Version:
2015
Subject:
English Dictionaries and Thesauri
Length:
54 words
cyclic AMP

cyclic AMP  

A derivative of ATP that is widespread in cells as a second messenger in many biochemical reactions induced by hormones. Binding of the hormone to its receptor on the cell surface activates G ...
dibutyryl cyclic AMP

dibutyryl cyclic AMP  

Reference type:
Overview Page
(db-cAMP)An analogue of cAMP often used experimentally because it probably enters cells more readily and is less rapidly hydrolysed.
cyclic AMP phosphodiesterase

cyclic AMP phosphodiesterase  

(number EC 3.1.4.17 shared with cyclic GMP phosphodiesterase); recommended name: 3′,5′‐cyclic‐nucleotide phosphodiesterase; an enzyme that catalyses the hydrolysis of a nucleoside 3′,5′‐cyclic ...
cyclic AMP receptor

cyclic AMP receptor  

Any of various receptor molecules that bind cyclic AMP, especially CRP (def. 2), a bacterial catabolite (gene) activator protein. Other examples are the signalling receptors of the slime mould, ...
cyclic AMP-dependent protein kinase

cyclic AMP-dependent protein kinase  

or(abbr.: PKA) a protein kinase that is regulated by cyclic AMP (cAMP). In type I, the inactive form of the enzyme is composed of two regulatory and two catalytic ...
A-kinase

A-kinase  

An enzyme that phosphorylates target proteins in response to a rise in intracellular cyclic AMP. See cyclic AMP‐dependent protein kinase.

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