You are looking at 1-10 of 10 entries  for:

  • All: casein kinases x
clear all

View:

Overview

casein kinases

A group of kinases that preferentially phosphorylate acidic proteins such as caseins but can phosphorylate a large number of proteins. Casein kinase 1 (EC 2.7.11.1, multiple isoforms, ~415 ...

casein kinases

casein kinases   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...casein kinases A group of kinases that preferentially phosphorylate acidic proteins such as caseins but can phosphorylate a large number of proteins. Casein kinase 1 (EC 2.7.11.1, multiple isoforms, ~415 aa) participates in Wnt signalling and is a central component of the circadian clock. Casein kinase II (phosvitin, 215 aa) is part of a tetrameric complex that is also involved in Wnt signalling. It is thought to regulate a broad range of transcription factors and in the brain has been associated with long-term potentiation by phosphorylating proteins...

casein kinases

casein kinases  

A group of kinases that preferentially phosphorylate acidic proteins such as caseins but can phosphorylate a large number of proteins. Casein kinase 1 (EC 2.7.11.1, multiple isoforms, ~415 aa) ...
casein kinase I

casein kinase I   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
98 words

... kinase I any of a family of ubiquitously expressed monomeric serine/threonine protein kinases found in a variety of subcellular locations in all eukaryotic organisms from protozoa to humans. There are seven isoforms in human cells, and all contain a kinase domain flanked by divergent N‐ and C‐terminal extensions. They play roles in Wnt signalling, circadian rhythms, nuclear import, and progression of Alzheimer disease, and have a general preference for acidic substrates. The family is named after the first of two fractions to elute from an anion‐exchange...

N-(2-aminoethyl)isoquinoline-5-sulfonamide

N-(2-aminoethyl)isoquinoline-5-sulfonamide  

ora selective inhibitor of casein kinase I, protein kinase A, and, less potently, protein kinase C.
pacsins

pacsins  

Reference type:
Overview Page
A family of cytoplasmic adaptor phosphoproteins (protein kinase C and casein kinase substrate in neurons) that interact with dynamin, synaptojanin, and N-WASP, and are involved in vesicle ...
tau protein

tau protein  

Reference type:
Overview Page
A protein (352 aa with multiple isoforms) that copurifies with tubulin and coassembles into microtubules. It has tandem repeats of a tubulin binding domain. Tau isoforms are found in all cells and ...
N‐(2‐aminoethyl)isoquinoline‐5‐sulfonamide

N‐(2‐aminoethyl)isoquinoline‐5‐sulfonamide   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
19 words

...‐(2‐aminoethyl)isoquinoline‐5‐sulfonamide or H9 a selective inhibitor of casein kinase I, protein kinase A, and, less potently, protein kinase...

tau protein

tau protein   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...with tubulin and coassembles into microtubules. It has tandem repeats of a tubulin binding domain. Tau isoforms are found in all cells and are highly expressed in neurons where they associate with axonal microtubules. See MAPs ; tauopathy . Tau tubulin kinase (1244 aa) is a casein kinase type enzyme that will phosphorylate both tau and tubulin. Mutations are associated with spinocerebellar ataxia ...

pacsins

pacsins   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...pacsins A family of cytoplasmic adaptor phosphoproteins (protein kinase C and casein kinase substrate in neurons) that interact with dynamin, synaptojanin, and N-WASP, and are involved in vesicle trafficking. Pacsin 1 (434 aa), which is more strongly expressed in brain, interacts with huntingtin in a repeat length-sensitive manner, interacting more strongly with mutant huntingtin. Pacsin 2 (486 aa) and pacsin 3 (424 aa) are more ubiquitously expressed and do not interact with huntingtin. http://www.endocytosis.org/BARdomains/BARs.html Structural...

protein phosphatase

protein phosphatase   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
275 words

...activated by different histones and polylysine. These have a very high affinity for the tumour promoter okadaic acid . Human phosphatase 2A has a catalytic subunit of 309 amino acids. This enzyme can modulate the activities of phosphorylase kinase b , casein kinase 2, mitogen‐stimulated S6 kinase, and MAP‐2 kinase. It is a cytoplasmic enzyme that exists in several oligomeric forms, all of which contain a catalytic (C) subunit (36–38 kDa) associated with one or both of two putatively regulatory subunits, the A subunit (61–65 kDa) and the B subunit (51–55...

View: