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Overview

T-cell factor

(TCF) A family of transcription factors (lymphoid enhancer-binding factor (LEF), LEF/TCFs) that are important in the wnt/β-*catenin signalling cascade. The nomenclature is very ...

T-cell factor

T-cell factor   Quick reference

A Dictionary of Biomedicine (2 ed.)

Reference type:
Subject Reference
Current Version:
2019

...T-cell factor ( TCF ) A family of transcription factors ( lymphoid enhancer-binding factor ( LEF ), LEF/TCFs) that are important in the wnt / β ‎- catenin signalling cascade. The nomenclature is very confusing: TCF1 (T-cell specific transcription factor) is officially TCF7 (transcription factor 7) and is actually found in many tissues, not just T cells. The ‘official’ TCF1 (transcription factor 1) is hepatocyte nuclear factor 1 ( HNF1 , a homeobox transcription factor involved in regulating liver-specific genes and mutated in maturity onset diabetes of...

T‐cell growth factor

T‐cell growth factor   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
11 words

...‐cell growth factor abbr. : TCGF; an alternative name for interleukin 2...

T‐cell‐replacing factor

T‐cell‐replacing factor   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
15 words

...‐cell‐replacing factor abbr. : TRF; a former term for some interleukins. See interleukin 1 , interleukin 5...

secondary cytotoxic T cell‐inducing factor

secondary cytotoxic T cell‐inducing factor   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
13 words

...cytotoxic T cell‐inducing factor abbr. : SCIF; an alternative name for interleukin 2...

T-cell factor

T-cell factor  

Reference type:
Overview Page
(TCF)A family of transcription factors (lymphoid enhancer-binding factor (LEF), LEF/TCFs) that are important in the wnt/β-*catenin signalling cascade. The nomenclature is very confusing: TCF1 (T-cell ...
T-cell-replacing factor

T-cell-replacing factor  

abbr.: TRF; a former term for some interleukins. See interleukin 1, interleukin 5.
T-cell growth factor

T-cell growth factor  

abbr.: TCGF; an alternative name for interleukin 2.
secondary cytotoxic T cell-inducing factor

secondary cytotoxic T cell-inducing factor  

abbr.: SCIF; an alternative name for interleukin 2.
Revolution

Revolution   Reference library

An Oxford Companion to the Romantic Age

Reference type:
Subject Reference
Current Version:
2009
Subject:
History, modern history (1700 to 1945), Literature
Length:
5,734 words
Publisher:
Oxford University Press

...terms: either to accept the status quo, or to jeopardize the Englishman's liberties, his culture, and his civilization. If few saw the choice so bleakly when the Reflections were published in November 1790 , many were persuaded to do so by the second half of the decade. One factor in their thinking was, without doubt, the way that events in France seemed pantomimically to fulfil Burke's worst fears. The widespread massacre of prisoners in Paris in September 1792 , the outbursts of insurrection and civil war within France, the construction of the Terror,...

scatter factor

scatter factor  

Reference type:
Overview Page
A motility factor (motogen) that stimulates dispersal (scattering) of colonies of epithelial and endothelial cells as single cells. It is identical to hepatocyte growth factor, but is not mitogenic ...
helper factor

helper factor  

Reference type:
Overview Page
An obsolete term for a group of factors that were invoked to explain some of the cell–cell interactions involved in immune responses. Many cytokines and interleukins act as helper factors, but the ...
F+ cell

F+ cell  

A bacterial cell possessing a fertility (F) factor extrachromosomally in a plasmid. An F+ cell can donate the F factor to an F− cell during conjugation. If the F factor integrates into the bacterial ...
erythroid Krüppel-like factor

erythroid Krüppel-like factor  

Reference type:
Overview Page
An erythroid cell-specific zinc finger transcription factor (EKLF, 362 aa) that is important in differentiation of the megakaryocyte–erythroid progenitor cells: it inhibits the formation of ...
RE1-silencing transcription factor

RE1-silencing transcription factor  

Reference type:
Overview Page
A transcriptional repressor (REST, neuron-restrictive silencer factor, 1097 aa) that represses neuronal genes in non-neuronal tissues by binding to the neuron-restrictive silencer element. Also ...
keratinocyte growth factor

keratinocyte growth factor  

Reference type:
Overview Page
A single polypeptide chain (KGF, fibroblast growth factor 7, 194 aa) that is a potent mitogen for epithelial cells (including keratinocytes) but nonmitogenic for fibroblasts or endothelial cells. The ...
stem cell factor

stem cell factor  

A pleiotropic growth factor (SCF, steel factor in mice, mast cell growth factor, c-kit ligand, 245 aa) that acts in utero in germ cell and neural cell development, and in the adult is primarily a ...
mitogenesis

mitogenesis  

Reference type:
Overview Page
The process of stimulating cell proliferation; progression through the whole cell cycle, not just mitosis. Resting cells are usually considered to be in the G0 phase and so mitogens act to stimulate ...
Th-POK

Th-POK  

Reference type:
Overview Page
A zinc finger transcription factor (T-helper-inducing POZ/Krüppel-like factor, cKrox, 539 aa) that regulates the commitment of immature T-cell precursors to particular lineages. In mice the absence ...
GATA transcription factors

GATA transcription factors  

Reference type:
Overview Page
A family of zinc finger transcription factors that bind to the ‘GATA’ nucleotide motif. GATA1 protein (NFE1, Eryfl, GF-1, or EFya, 413 aa) regulates the switch from fetal to adult haemoglobin in ...
nuclear factor κB

nuclear factor κB  

(NFκB)A transcription factor involved in rapid cellular responses to stresses, such as injury or invading pathogens, and in many aspects of cell proliferation and survival. It is found in the cells ...

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