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GoLoco motif

GoLoco motif  

A 20‐residue protein sequence in some proteins that regulate G‐protein signalling via Gα0 and Gαi. It is present in two proteins required for asymmetric spindle positioning in Caenorhabditis elegans ...
Loco

Loco  

A protein of Drosophila that is homologous to the mammalian RGS12, which regulates G‐protein signalling via Gα0 and Gαi.
chromic compounds

chromic compounds  

Compounds containing chromium in a higher (+3 or +6) oxidation state; e.g. chromic oxide is chromium(VI) oxide (CrO3).
G protein

G protein  

Any one of a group of proteins that relay signals in mammalian cells (see signal transduction). They occur on the inner surface of the plasma membrane and transmit signals from receptors on the outer ...
RGG box

RGG box  

A peptide sequence (20–25 amino acids) present in some proteins, often in association with the RNA‐binding domains found in FMR1. It contains repeats of Arg—Gly—Gly, often interspersed with aromatic ...
fish oil

fish oil  

Fish oils contain long-chain polyunsaturated fatty acids which are protective against heart disease and stroke. The two main fatty acids are EPA (eicosapentaenoic acid; C20:5 ω3) and DHA ...
biochemical engineering

biochemical engineering  

orthe scientific discipline underlying the industrial processing of biological materials, e.g. fermentation‐based pharmaceuticals, foods, and effluents.
adrenocortical

adrenocortical  

Of, pertaining to, or derived from the cortex of the adrenal gland, e.g. adrenocortical hormone. See adrenal androgen, corticosteroid.
Cori's disease

Cori's disease  

an alternative name for type III glycogen disease. [After G. T. Cori who first described it in 1953.]
cell cortex

cell cortex  

The part of the microtrabecular lattice lying just under the outer cell membrane of certain protozoans, e.g. paramecia.
cyanogen

cyanogen  

A colourless gas, (CN)2, with a pungent odour; soluble in water, ethanol, and ether; d. 2.335 g dm−3; m.p. –27.9°C; b.p. –20.7°C. The compound is very toxic. It may be prepared in the laboratory by ...
debranching enzyme

debranching enzyme  

Any enzyme that catalyses the cleavage of branch points in particular branched biopolymers, e.g. isoamylase, oligo‐1,6‐glucosidase and pullulanase.
premurein-leader peptidase

premurein-leader peptidase  

EC 3.4.99.35; other names: prolipoprotein‐signal peptidase; signal peptidase II; SPase II. An enzyme that cleaves a single bond between Gly20 and alkylated Cys21 in a bacterial lipoprotein, detaching ...
singly labelled

singly labelled  

Describing a specifically labelled compound containing only one isotopically modified atom in a uniquely specified position, e.g CH3−CH[2H]−OH.
SQL

SQL  

abbr. for symbolic query language; a query language used with relational databases, e.g. SYBASE. It is often pronounced ‘sequel’.
subsite

subsite  

A site, e.g. on a protein, that has a specific function within the overall function of a larger site.
ternary complex

ternary complex  

Any complex formed between three chemical entities, e.g. a complex formed between an enzyme and two substrate molecules.
TM7 receptor

TM7 receptor  

orany plasma membrane receptor or other protein that contains seven transmembrane segments, each of 20–25 amino acids. Included are the family of G‐protein associated membrane receptors and the TRP ...
vectorial enzyme

vectorial enzyme  

Any enzyme, such as one fixed in a membrane, that is directional in its action, e.g. sodium/potassium ATPase.
inhibit

inhibit  

To prevent the occurrence of an event, e.g. to use a logic gate to inhibit another signal. Compare enable.

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