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A20

A cytoplasmic zinc finger protein (790 aa) that inhibits NFκB activity and TNF-mediated programmed cell death. The expression of the A20 mRNA is upregulated by TNFα. It is a dual function ...

A20

A20   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...A20 A cytoplasmic zinc finger protein (790 aa) that inhibits NF κ ‎B activity and TNF-mediated programmed cell death. The expression of the A20 mRNA is upregulated by TNF α ‎. It is a dual function enzyme with deubiquitinating and ubiquitin ligase activity that triggers degradation of RIP ( receptor interacting protein kinase ) an essential mediator of the TNF receptor-1 signalling...

A20

A20  

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A cytoplasmic zinc finger protein (790 aa) that inhibits NFκB activity and TNF-mediated programmed cell death. The expression of the A20 mRNA is upregulated by TNFα. It is a dual function enzyme with ...
STE20 kinases

STE20 kinases  

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A group of serine/threonine kinases involved in regulating a range of processes including the cell cycle, apoptosis, and stress responses. Yeast Ste20p (sterile 20 protein) is a mitogen-activated ...
p20

p20  

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1. p20-ARC One of the subunits of ARP2/3.2. p20-CGGBP (CGG-binding protein1) A protein that binds to the unmethylated form of the trinucleotide repeat in the 5′ UTR that is a feature of fragile X ...
interleukin-20

interleukin-20  

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(IL-20)One of the IL-10 family of cytokines, produced by monocytes and keratinocytes, and an autocrine factor for keratinocytes. The receptor is up-regulated dramatically in psoriatic skin.
Alu

Alu  

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1. A type II restriction endonuclease, isolated from Arthrobacter luteus.2. Highly repetitive short repeat sequences (Alu repeats, short interspersed elements, SINEs) found in large numbers (100 ...
abort

abort  

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(ă-bort)1 to terminate a process or disease before its full course has been run.2 to remove or expel an embryo or fetus from the uterus before it is capable of independent existence. See abortion.
frying

frying  

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Cooking foods with oil at temperatures well above the boiling point of water. Deep frying, in which a food is completely immersed in oil, reaches a temperature around 185 °C. Nutrient losses are less ...
Canadian trunk strength test

Canadian trunk strength test  

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A test of the muscular endurance of the abdominal muscles (figure 20).▪ Lie on your back with the knees flexed at 90 degrees and your fingertips touching a strip of masking tape placed perpendicular ...
enamelysin

enamelysin  

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A metallopeptidase (matrix metallopeptidase-20, MMP-20, 483 aa) that has specificity for amelogenin.
SLK

SLK  

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A microtubule-associated STE20-like kinase (1235 aa, of the germinal centre subfamily of STE20-like kinases) that is required for focal adhesion turnover and cell migration downstream of the ...
metzincins

metzincins  

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A clan of metallopeptidases (zinc endopeptidases) of which pappalysins are one family. Other members include astacins and matrix ...
CD antigens

CD antigens  

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The ‘cluster of differentiation’ antigens that were originally marker antigens found on different classes of lymphocytes using monoclonal antibodies. The CD nomenclature was introduced as a means of ...
falloposcopy

falloposcopy  

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n. observation of the interior of a Fallopian tube using a falloposcope introduced via a hysteroscope (see hysteroscopy).
protein rating

protein rating  

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Used in Canadian food labelling regulations to assess the overall protein quality of a food. It is Protein Efficiency Ratio multiplied by the protein content of food (per cent) multiplied by the ...
grillade à l'ardoise

grillade à l'ardoise  

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Andorran method of cooking on a red-hot roof slate heated over a wood fire (French: ardoise, slate).
bone, trabecular

bone, trabecular  

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The spongy bone, consisting of a structural mesh of trabeculae forming an internal scaffold, found mainly at the ends of long bones, in vertebral bodies, and flat bones, accounting for some 20% of ...
à la king

à la king  

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Dish served in a rich cream sauce (often flavoured with sherry) and including mushrooms and green peppers.
acoustic incident

acoustic incident  

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A sudden unexpected noise transmitted through a telephone handset or headset with the potential of triggering acoustic shock.
flat-panel detector

flat-panel detector  

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A piece of equipment used instead of a conventional X-ray film to acquire the image in digital radiography.

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