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20/20

Subject: Music

This US group was formed in Los Angeles, California, in 1978 by Steve Allen (guitar, vocals) and Ron Flynt (bass, vocals), two expatriate musicians from Tulsa, Oklahoma. Drummer Mike Gallo ...

p20

p20   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...p20 1. p20-ARC One of the subunits of ARP2/3 . 2. p20-CGGBP (CGG-binding protein1) A protein that binds to the unmethylated form of the trinucleotide repeat in the 5′ UTR that is a feature of fragile X syndrome . 3. p20-CCAAT enhancer-binding protein β ‎ ( CEBP β ‎), a truncated C/EBP β ‎...

interleukin-20

interleukin-20   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...interleukin-20 ( IL-20 ) One of the IL-10 family of cytokines, produced by monocytes and keratinocytes, and an autocrine factor for keratinocytes. The receptor is up-regulated dramatically in psoriatic skin....

A20

A20   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...A20 A cytoplasmic zinc finger protein (790 aa) that inhibits NF κ ‎B activity and TNF-mediated programmed cell death. The expression of the A20 mRNA is upregulated by TNF α ‎. It is a dual function enzyme with deubiquitinating and ubiquitin ligase activity that triggers degradation of RIP ( receptor interacting protein kinase ) an essential mediator of the TNF receptor-1 signalling...

STE20 kinases

STE20 kinases   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...STE20 kinases A group of serine/threonine kinases involved in regulating a range of processes including the cell cycle, apoptosis, and stress responses. Yeast Ste20p (sterile 20 protein) is a mitogen-activated protein kinase kinase kinase kinase (MAP4K) involved in the mating pathway. The human homologues, of which there are 28, have a conserved kinase domain but a diversity of additional domains involved in interactions with signalling systems and cytoskeletal-regulatory proteins. The Ste20 group kinases are further divided into the p21-activated kinase (...

enamelysin

enamelysin   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
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2019

...enamelysin A metallopeptidase (matrix metallopeptidase-20, MMP-20, 483 aa) that has specificity for amelogenin...

Alu

Alu   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...short repeat sequences ( Alu repeats , short interspersed elements, SINEs) found in large numbers (100 000–500 000) in the human genome, the most abundant mobile elements (retrotransposons) in the human genome. http://batzerlab.lsu.edu/Publications/Batzer%20and%20Deininger%202002%20Nature%20Reviews%20Genetics.pdf Review on Alu repeats; Nature May...

SLK

SLK   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...SLK A microtubule-associated STE20 -like kinase (1235 aa, of the germinal centre subfamily of STE20-like kinases) that is required for focal adhesion turnover and cell migration downstream of the FAK / c-src ...

metzincins

metzincins   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...metzincins A clan of metallopeptidases (zinc endopeptidases) of which pappalysins are one family. Other members include astacins and matrix metallopeptidase . http://www.copewithcytokines.de/cope.cgi?key=Metalloproteinase%20MiniCOPE%20Dictionary The Cytokines & Cells Online Pathfinder Encyclopedia contains further...

rituximab

rituximab   Quick reference

A Dictionary of Biomedicine (2 ed.)

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2019

...rituximab A monclonal antibody, directed against CD20, used to treat non-Hodgkin’s lymphoma. TN ...

RNA polymerase mediator complex

RNA polymerase mediator complex   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...RNA polymerase mediator complex A multiprotein complex of ~20 polypeptides, physically associated with RNA polymerase II and essential for transcriptional...

tryptophan

tryptophan   Quick reference

A Dictionary of Biomedicine (2 ed.)

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2019

...tryptophan ( Trp, W ) One of the 20 amino acids (204 Da) found in proteins and an essential component of the diet for...

microsomes

microsomes   Quick reference

A Dictionary of Biomedicine (2 ed.)

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2019

...microsomes Small vesicles (20–200 nm diameter) produced when cells are disrupted. Unless fractionated may contain membrane from various organelles, though mostly the endoplasmic reticulum...

oligonucleotide

oligonucleotide   Quick reference

A Dictionary of Biomedicine (2 ed.)

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2019

...oligonucleotide A linear sequence of nucleotides joined by phosphodiester bonds, conventionally up to 20 nucleotides, longer polymers being referred to as polynucleotides...

lactacystin

lactacystin   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Current Version:
2019

...lactacystin A compound isolated from Streptomyces sp., widely used experimentally as an inhibitor of the 20S proteosome...

alpha rhythm

alpha rhythm   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...alpha rhythm A regular pattern of waves (alpha waves, 8–12 Hz, 20–100 mV) observed in the electroencephalogram ( EEG ) of waking inactive...

phosphocreatine

phosphocreatine   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...phosphocreatine ( creatine phosphate ) A compound found at high concentration (~20 mmol/L) in striated muscle where it acts as an energy reserve, buffering ATP levels through the action of creatine kinase...

Tween

Tween   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...Tween A family of detergents often used for solubilizing membrane proteins or for lysing mammalian cells. Tween variants (Tween-20, -40, -60, -80) have fatty acid moieties of differing chain...

A cells

A cells   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...A cells ( α ‎ cells ) Cells of the islets of Langerhans in the pancreas. They constitute around 20% of the population and secrete glucagon . See beta cells ; D cells...

amino acid

amino acid   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...amino acid An organic acid carrying an amino group. Proteins are linear polymers of the l -forms of ~20 common amino acids linked by peptide bonds . See Appendix 3...

SPAK

SPAK   Quick reference

A Dictionary of Biomedicine (2 ed.)

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Subject Reference
Current Version:
2019

...SPAK A serine/threonine kinase (Ste20/SPS-1-related proline, alanine-rich kinase, 547 aa) that will phosphorylate and activate NKCC1 (Na + -K + -2Cl − cotransporter-1). SPAK and OSR1 (oxidative stress-responsive kinase-1), are activated by WNKs...

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