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polyposis

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adenosquamous

adenosquamous  

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Describing a benign tumour of epithelial origin (an adenoma) in which cells have flattened (squamous) morphology, rather than being cuboidal or columnar.
catenins

catenins  

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Proteins that are associated with the cytoplasmic domain of adhesion molecules such as cadherins and link them to the cytoskeleton. A second role is in regulating transcription factors. α-Catenin ...
desmoid tumour

desmoid tumour  

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A dense connective-tissue tumour with a dangerous propensity for repeated local recurrence after treatment. Intra-abdominal desmoids have an association with familial adenomatous polyposis (FAP).
EB1

EB1  

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A member of the RP/EB family of proteins (adenomatous polyposis coli-binding protein EB1, microtubule-associated protein, RP/EB family member 1, MAPRE1, 268 aa) that was isolated in a two-hybrid ...
familial

familial  

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adj. describing a condition or character that is found in some families but not in others. It is often inherited.
Gardner's syndrome

Gardner's syndrome  

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A variant form of familial adenomatous polyposis in which polyps in the colon are associated with fibromas and osteomas (benign tumours), especially of the skull and jaw, and multiple sebaceous ...
gastric cancer

gastric cancer  

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Carcinoma of the stomach, probably the second most common carcinoma. Several genes may be associated with an increased risk of gastric cancer and there are various inherited cancer predisposition ...
gastroenterological disorders

gastroenterological disorders  

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Many disorders of the gastrointestinal tract are caused by toxins (enterotoxins) in food or produced by infectious agents such as Enterobacter, Vibrio cholerae, enteroviruses (e.g. norovirus, ...
hereditary nonpolyposis colorectal cancer

hereditary nonpolyposis colorectal cancer  

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(HNPCC, Lynch syndrome) an inherited disorder in which there is an increased incidence of colorectal polyp formation, although to a lesser extent than in familial adenomatous polyposis (FAP). HNPCC ...
Peutz–Jeghers syndrome

Peutz–Jeghers syndrome  

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A hereditary disorder in which the presence of multiple polyps in the lining of the small intestine (intestinal polyposis) is associated with pigmented areas (similar to freckles) around the lips, on ...
polyp

polyp  

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1. A growth, usually benign, that projects from a mucous membrane and resembles (vaguely) (2).2. The sessile stage of the life cycle of some coelenterates (e.g. Hydra), a cylindrical body attached to ...
tubulovillous adenoma

tubulovillous adenoma  

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A type of polyp that arises in the colon and rectum and can undergo malignant transformation, usually over a period of years, although this can occur more rapidly in familial polyposis syndromes.
tumour suppressor

tumour suppressor  

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Generally a gene (antioncogene, cancer susceptibility gene) encoding a negative regulator of the cell cycle, e.g. an inhibitor of a growth factor signalling system, that must be mutated or otherwise ...

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