Overview

Peutz–Jeghers syndrome

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gastric cancer

gastric cancer  

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Carcinoma of the stomach, probably the second most common carcinoma. Several genes may be associated with an increased risk of gastric cancer and there are various inherited cancer predisposition ...
LKB1

LKB1  

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A kinase (serine/threonine kinase 11, STK11, 433 aa) mutated in Peutz–Jeghers syndrome that interacts with p53; deficiency is associated with defective apoptosis.
melanin pigmentation

melanin pigmentation  

A change in the amount of melanin produced. It may be developmental (see melanocytic naevus; Peutz-Jeghers syndrome; café au lait spots) or acquired as the result of systemic disease (see Addison's ...
polyp

polyp  

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1. A growth, usually benign, that projects from a mucous membrane and resembles (vaguely) (2).2. The sessile stage of the life cycle of some coelenterates (e.g. Hydra), a cylindrical body attached to ...
polyposis

polyposis  

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n. a condition in which numerous polyps form in an organ or tissue. Familial adenomatous polyposis (FAP) is a hereditary disease (caused by a defective dominant gene) in which multiple adenomas ...

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