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Overview

cyclic AMP

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adenosine

adenosine  

A nucleoside comprising one adenine molecule linked to a d-ribose sugar molecule. The phosphate-ester derivatives of adenosine, AMP, ADP, and ATP, are of fundamental biological importance as carriers ...
adenylate cyclase

adenylate cyclase  

The enzyme that catalyses the formation of cyclic AMP. It is bound to the inner surface of the plasma membrane. Many hormones and other chemical messengers exert their physiological effects by ...
A-kinase

A-kinase  

An enzyme that phosphorylates target proteins in response to a rise in intracellular cyclic AMP. See cyclic AMP‐dependent protein kinase.
AMP

AMP  

Reference type:
Overview Page
(adenosine monophosphate) a compound containing adenine, ribose, and one phosphate group. AMP occurs in cells and is involved in processes requiring the transfer of energy (see atp).
ATP

ATP  

Reference type:
Overview Page
(adenosine triphosphate) a compound that contains adenine, ribose, and three phosphate groups and occurs in cells. The chemical bonds of the phosphate groups store energy needed by the cell, for ...
cellular signal transduction

cellular signal transduction  

The pathways through which cells receive external signals and transmit, amplify, and direct them internally. The pathway begins with cell-surface receptors (q.v.) and may end in the cell nucleus with ...
CREB

CREB  

The abbreviation for cyclic AMP response element binding proteins. These proteins are required for the consolidation of short-term memory into long-term memory. Genes encoding CREBs have been cloned ...
cyclic AMP

cyclic AMP   Reference library

Oxford Dictionary of Biochemistry and Molecular Biology (2 ed.)

Reference type:
Subject Reference
Current Version:
2008
Subject:
Science and technology, Life Sciences
Length:
12 words

abbr. for adenosine 3′,5′‐phosphate. See also adenylate cyclase.

cyclic GMP

cyclic GMP  

Cyclic guanosine monophosphate, a compound that is analogous to cyclic AMP and that keeps sodium channels open in the outer membranes of rods and cones in the retina when its ring structure is ...
cyclic AMP

cyclic AMP   Quick reference

The Oxford Dictionary of Sports Science & Medicine (3 ed.)

Reference type:
Subject Reference
Current Version:
2007
An important intracellular chemical that mediates intracellular responses to some non-steroid hormones: it acts as a second messenger. Cyclic AMP is formed from ATP by the action of ... More
MEM 1414

MEM 1414  

Memory 1414, a smart drug developed in the 1990s that inhibits phosphodiesterase type 5 and thereby reduces the metabolization of cyclic AMP and increases the prevalence of CREB in neurons in the ...
milrinone

milrinone  

An inhibitor of phosphodiesterase III which leads to elevation of cAMP levels. Has positive inotropic and vasodilatory effects and is sometimes used in treatment of heart failure if other drugs fail. ...
protein kinase A

protein kinase A  

(PKA)A family of serine/threonine kinases (PKA, cAMP-dependent protein kinase, EC 2.7.11.1) regulated by the level of cyclic AMP in the cell. They have two catalytic subunits and two regulatory ...
second messenger

second messenger  

Reference type:
Overview Page
An organic molecule that acts within a cell to initiate the response to a signal carried by a chemical messenger (e.g. a hormone) that does not itself enter the cell. Examples of second messengers ...

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