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date: 10 August 2020

interleukin-10 (IL-10) 

Source:
A Dictionary of Biomedicine
Author(s):

John Lackie

, Brian NationBrian Nation

A cytokine (cytokine synthesis inhibiting factor, CSIF, TGIF, a homodimer of 160 aa subunits) produced by Th2 cells, some B cells, and LPS-activated monocytes. IL-10 regulates cytokine production by a range of other cells and is an inhibitor of immune responses. Individuals show marked variation in IL-10 secretion in response to LPS and the variation has a strong genetic component. The ... ...

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