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Barker hypothesis

Syn: thrifty phenotype hypothesis. A hypothesis proposed in 1990 by the British epidemiologist David Barker (b. 1939) that intrauterine growth retardation, low birth weight, and premature ...

Barker hypothesis

Barker hypothesis   Quick reference

A Dictionary of Public Health (2 ed.)

Reference type:
Subject Reference
Current Version:
2018

...Barker hypothesis ( thrifty phenotype hypothesis ) A hypothesis proposed in 1990 by the British epidemiologist David Barker ( 1938–2013 ) that intrauterine growth retardation, low birth weight, and premature birth have a causal relationship to the origins of hypertension, coronary heart disease, and non-insulin-dependent diabetes, in middle age. The evidence is presented in Barker's book Fetal and Infant Origins of Adult Disease ( 1992 ). See also developmental origins of health and disease . ...

Barker hypothesis

Barker hypothesis  

Syn: thrifty phenotype hypothesis. A hypothesis proposed in 1990 by the British epidemiologist David Barker (b. 1939) that intrauterine growth retardation, low birth weight, and premature birth have ...
A Midsummer Night’s Dream

A Midsummer Night’s Dream   Reference library

Michael Dobson and Anthony Davies

The Oxford Companion to Shakespeare (2 ed.)

Reference type:
Subject Reference
Current Version:
2015
Subject:
Literature, Shakespeare studies and criticism, Performing arts, Theatre
Length:
3,220 words
Publisher:
Oxford University Press
Illustration(s):
1

...included an 8-year-old Ellen Terry entering as Robin Goodfellow on a pop-up mushroom. This tradition of spectacle peaked in Beerbohm Tree ’s production ( 1900 ): his wood featured real live rabbits. More indicative of 20th-century Dreams to come was Harley Granville-Barker ’s controversial 1914 production at the Savoy, with its gilded, other-worldly, puppet-like fairies. Since then the play has been both immensely popular (one of the most frequently revived in the canon, especially in outdoor venues: it appeared every year at the Open Air...

programming, metabolic

programming, metabolic  

Reference type:
Overview Page
The idea that nutrition in utero (and hence maternal nutrition) and early post-natal life leads to epigenetic programming of metabolism, and predisposes to chronic disease in later life. Sometimes ...
intrauterine growth retardation

intrauterine growth retardation  

A condition in which fetal development proceeds more slowly than normal, developmental milestones are reached later than expected, and prospects of delivery of a healthy full-term infant are ...
market value

market value  

Reference type:
Overview Page
Subject:
Law
*Inheritance tax is charged on the market value of property at death and capital gains tax is charged on the market value of an asset at the time of disposal. In both cases, statute gives only a ...
non-insulin-dependent diabetes

non-insulin-dependent diabetes  

(NIDDM)Syn: adult-onset diabetes, type 2 diabetes. This form of adult-onset diabetes is commonly associated with obesity and usually responds well to a strict dietary regimen; it does not usually ...
cultural relativism

cultural relativism  

Reference type:
Overview Page
Subject:
Religion
[Th]The position that there is no universal standard to measure cultures by, and that all cultures are equally valid and must be understood in their own terms.
life course

life course  

The natural history of human life. A term for conditions that evolve over a large part or all of the life span from infancy, or even from conception, through adolescence, adult life, and senescence, ...
programming, metabolic

programming, metabolic   Quick reference

A Dictionary of Food and Nutrition (4 ed.)

Reference type:
Subject Reference
Current Version:
2014

...metabolic The idea that nutrition in utero (and hence maternal nutrition) and early post-natal life leads to epigenetic programming of metabolism, and predisposes to chronic disease in later life. Sometimes known as the Barker hypothesis, since it was first enunciated by David Barker ( 1938–2013 ). See also epigenetics...

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